{"id":1898,"date":"2018-04-22T20:33:00","date_gmt":"2018-04-23T01:33:00","guid":{"rendered":"https:\/\/restruct-lgmd-2021.pantheonsite.io\/?p=1898"},"modified":"2018-04-22T20:33:00","modified_gmt":"2018-04-23T01:33:00","slug":"lgmd-researcher-rita-perlingeiro","status":"publish","type":"post","link":"https:\/\/www.lgmd-info.org\/it\/researcher-interview\/2018\/04\/22\/lgmd-researcher-rita-perlingeiro\/","title":{"rendered":"RICERCATORE LGMD: Rita Perlingeiro"},"content":{"rendered":"

LGMD \"Intervista a riflettori accesi sulla ricerca<\/strong><\/span><\/h2>\n

RICERCATORE LGMD<\/strong>: Rita Perlingeiro\"\"<\/a><\/p>\n

Affiliazione:<\/strong> Universit\u00e0 del Minnesota<\/p>\n

Ruolo o posizione:\u00a0 <\/strong>Professore di Medicina<\/p>\n

Che tipo di istruzione e formazione ha seguito per arrivare alla sua posizione attuale?<\/strong><\/p>\n

Dottorato di ricerca in Fisiologia presso l'Universit\u00e0 di Campinas (UNICAMP) a San Paolo, Brasile, seguito da studi post-dottorato presso il Whitehead Institute del MIT, Cambridge-MA.<\/p>\n

Cosa l'ha spinta a intraprendere una carriera nella ricerca e nello studio della distrofia muscolare in particolare?<\/strong><\/p>\n

Volevo diventare uno scienziato fin da bambino. Nel corso della mia carriera, la motivazione principale \u00e8 stata il desiderio di avere un impatto sulla vita delle persone attraverso la nostra ricerca.<\/p>\n

Quali argomenti state studiando?<\/strong><\/p>\n

L'argomento principale della ricerca nel nostro laboratorio \u00e8 lo sviluppo di terapie basate sulle cellule staminali per le distrofie muscolari, e questo include una migliore comprensione della firma molecolare dei progenitori miogenici derivati da cellule staminali pluripotenti e delle cellule staminali incistate, dei segnali che permettono a queste cellule di localizzarsi nei muscoli malati al momento del trapianto sistemico e di promuovere la rigenerazione muscolare, correzione genica di cellule staminali pluripotenti indotte (iPS) specifiche per il paziente con LGMD per valutare il potenziale di una terapia autologa basata sulle cellule staminali e studi di ottimizzazione per la scalabilit\u00e0, la produzione e la sicurezza dei progenitori miogenici derivati da cellule staminali pluripotenti per applicazioni terapeutiche.<\/p>\n

In che modo il suo lavoro aiuter\u00e0 i pazienti? \u00c8 di natura pi\u00f9 scientifica o potrebbe diventare un trattamento per le LGMD o per i medici in generale?<\/strong><\/p>\n

Quando abbiamo iniziato questi studi nel 2004, si trattava di pura scienza di base, ma con il progredire della ricerca nel corso degli anni, riteniamo di essere ora molto pi\u00f9 vicini a tradurre questo approccio in un potenziale trattamento per la LGMD e altre MD. Nel 2017 abbiamo avuto un incontro pre-IND con la FDA per allineare i nostri obiettivi a breve e lungo termine.<\/p>\n

Cosa vorrebbe che i pazienti e gli altri interessati alla LGMD sapessero sulla ricerca (sui vostri progetti e sul campo in generale)?<\/strong><\/p>\n

Ci sono molti ostacoli e molte incognite sulla strada per portare un nuovo trattamento terapeutico per la sperimentazione della MD, ma il nostro laboratorio e altri stanno lavorando senza paura verso questo obiettivo.<\/p>\n

Cosa la ispira a continuare a lavorare in questo campo? <\/strong><\/p>\n

La possibilit\u00e0 che il nostro lavoro possa fare la differenza nella vita dei pazienti con MD.<\/p>\n

In che modo i pazienti possono incoraggiarvi e aiutare il vostro lavoro?<\/strong><\/p>\n

La forza e la speranza dei pazienti MD ci incoraggiano costantemente. Nel corso degli anni, i pazienti hanno aiutato il nostro lavoro attraverso la donazione di tessuti e il sostegno finanziario e siamo grati per il loro supporto.<\/p>\n

 <\/p>\n

* * * Vi invitiamo a mettere MI PIACE, COMMENTARE e CONDIVIDERE questo post per contribuire a sensibilizzare l'opinione pubblica sulla LGMD!<\/p>\n

* * * Per saperne di pi\u00f9 sulla distrofia muscolare della cintura degli arti (LGMD), visitate il nostro sito web all'indirizzo: https:\/\/lgmd-info.org<\/a>\u00a0 <\/u><\/p>","protected":false},"excerpt":{"rendered":"

LGMD “Spotlight Interview on Research\u201d LGMD RESEARCHER: Rita Perlingeiro Affiliation: […]<\/p>","protected":false},"author":1,"featured_media":1897,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[91,92],"tags":[],"class_list":["post-1898","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-researcher-interview","category-researcher"],"acf":[],"yoast_head":"\nLGMD RESEARCHER: Rita Perlingeiro - LGMD Awareness Foundation<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.lgmd-info.org\/it\/researcher-interview\/2018\/04\/22\/lgmd-researcher-rita-perlingeiro\/\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"LGMD RESEARCHER: Rita Perlingeiro - 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