{"id":1898,"date":"2018-04-22T20:33:00","date_gmt":"2018-04-23T01:33:00","guid":{"rendered":"https:\/\/restruct-lgmd-2021.pantheonsite.io\/?p=1898"},"modified":"2018-04-22T20:33:00","modified_gmt":"2018-04-23T01:33:00","slug":"lgmd-researcher-rita-perlingeiro","status":"publish","type":"post","link":"https:\/\/www.lgmd-info.org\/pl\/researcher-interview\/2018\/04\/22\/lgmd-researcher-rita-perlingeiro\/","title":{"rendered":"BADACZ LGMD: Rita Perlingeiro"},"content":{"rendered":"

LGMD \"Wywiad w centrum uwagi na temat bada\u0144\"<\/strong><\/span><\/h2>\n

BADACZ LGMD<\/strong>: Rita Perlingeiro\"\"<\/a><\/p>\n

Przynale\u017cno\u015b\u0107:<\/strong> Uniwersytet Minnesota<\/p>\n

Rola lub stanowisko:\u00a0 <\/strong>Profesor medycyny<\/p>\n

Jakie wykszta\u0142cenie i szkolenie zdoby\u0142e\u015b, aby osi\u0105gn\u0105\u0107 obecne stanowisko?<\/strong><\/p>\n

Doktorat z fizjologii na Uniwersytecie Campinas (UNICAMP) w Sao Paulo w Brazylii, a nast\u0119pnie studia podoktoranckie w Instytucie Whitehead na MIT w Cambridge-MA.<\/p>\n

Co sprawi\u0142o, \u017ce zdecydowa\u0142e\u015b si\u0119 na karier\u0119 naukow\u0105, a w szczeg\u00f3lno\u015bci na badanie dystrofii mi\u0119\u015bniowej?<\/strong><\/p>\n

Chcia\u0142em zosta\u0107 naukowcem, odk\u0105d by\u0142em ma\u0142ym dzieckiem. Przez ca\u0142\u0105 moj\u0105 karier\u0119 g\u0142\u00f3wn\u0105 motywacj\u0105 by\u0142o pragnienie wywierania wp\u0142ywu na \u017cycie ludzi poprzez nasze badania.<\/p>\n

Jakie tematy studiujesz?<\/strong><\/p>\n

G\u0142\u00f3wnym tematem bada\u0144 w naszym laboratorium jest rozw\u00f3j terapii opartych na kom\u00f3rkach macierzystych w leczeniu dystrofii mi\u0119\u015bniowych, w tym lepsze zrozumienie molekularnej sygnatury progenitor\u00f3w miogennych pochodz\u0105cych z pluripotencjalnych kom\u00f3rek macierzystych i wszczepionych kom\u00f3rek macierzystych, sygna\u0142\u00f3w, kt\u00f3re umo\u017cliwiaj\u0105 tym kom\u00f3rkom powr\u00f3t do chorych mi\u0119\u015bni po przeszczepie og\u00f3lnoustrojowym i promowanie regeneracji mi\u0119\u015bni, korekcja gen\u00f3w indukowanych pluripotencjalnych kom\u00f3rek macierzystych (iPS) specyficznych dla pacjenta z LGMD w celu oceny potencja\u0142u autologicznej terapii opartej na kom\u00f3rkach macierzystych oraz badania optymalizacyjne dotycz\u0105ce skalowalno\u015bci, produkcji i bezpiecze\u0144stwa progenitor\u00f3w miogennych pochodz\u0105cych z pluripotencjalnych kom\u00f3rek macierzystych do zastosowa\u0144 terapeutycznych.<\/p>\n

W jaki spos\u00f3b Twoja praca pomo\u017ce pacjentom? Czy ma ona bardziej naukowy charakter, czy te\u017c mo\u017ce sta\u0107 si\u0119 metod\u0105 leczenia LGMD lub og\u00f3lnie lekarzy?<\/strong><\/p>\n

Kiedy rozpocz\u0119li\u015bmy te badania w 2004 roku, mia\u0142y one charakter czysto naukowy, ale w miar\u0119 post\u0119pu naszych bada\u0144 na przestrzeni lat czujemy, \u017ce jeste\u015bmy teraz znacznie bli\u017cej prze\u0142o\u017cenia tego podej\u015bcia na potencjalne leczenie LGMD i innych chor\u00f3b uk\u0142adu mi\u0119\u015bniowo-szkieletowego. W 2017 r. spotkali\u015bmy si\u0119 z FDA w celu uzgodnienia naszych kr\u00f3tko- i d\u0142ugoterminowych cel\u00f3w.<\/p>\n

Co chcia\u0142by\u015b, aby pacjenci i inne osoby zainteresowane LGMD wiedzia\u0142y o badaniach (Twoich w\u0142asnych projektach i og\u00f3lnie o tej dziedzinie)?<\/strong><\/p>\n

Istnieje wiele przeszk\u00f3d i wiele niewiadomych na drodze do wprowadzenia nowego leczenia terapeutycznego w testach MD, ale nasze laboratorium i inni nieustraszenie pracuj\u0105 nad tym celem.<\/p>\n

Co inspiruje Ci\u0119 do dalszej pracy w tej dziedzinie? <\/strong><\/p>\n

Mo\u017cliwo\u015b\u0107, \u017ce nasza praca mo\u017ce zmieni\u0107 \u017cycie pacjent\u00f3w z MD.<\/p>\n

W jaki spos\u00f3b pacjenci mog\u0105 Ci\u0119 zach\u0119ci\u0107 i pom\u00f3c Ci w pracy?<\/strong><\/p>\n

Si\u0142a i nadzieja pacjent\u00f3w MD nieustannie dodaj\u0105 nam otuchy. Przez lata pacjenci pomagali nam w naszej pracy poprzez oddawanie tkanek i wsparcie finansowe, za co jeste\u015bmy im wdzi\u0119czni.<\/p>\n

 <\/p>\n

* * * Prosimy o LIKE, COMMENT i SHARE tego postu, aby pom\u00f3c zwi\u0119kszy\u0107 \u015bwiadomo\u015b\u0107 na temat LGMD!<\/p>\n

* * * Aby dowiedzie\u0107 si\u0119 wi\u0119cej o dystrofii mi\u0119\u015bniowej obr\u0119czy ko\u0144czyny (LGMD), odwied\u017a nasz\u0105 stron\u0119 internetow\u0105 pod adresem: https:\/\/lgmd-info.org<\/a>\u00a0 <\/u><\/p>","protected":false},"excerpt":{"rendered":"

LGMD “Spotlight Interview on Research\u201d LGMD RESEARCHER: Rita Perlingeiro Affiliation: […]<\/p>","protected":false},"author":1,"featured_media":1897,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[91,92],"tags":[],"class_list":["post-1898","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-researcher-interview","category-researcher"],"acf":[],"yoast_head":"\nLGMD RESEARCHER: Rita Perlingeiro - LGMD Awareness Foundation<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.lgmd-info.org\/pl\/researcher-interview\/2018\/04\/22\/lgmd-researcher-rita-perlingeiro\/\" \/>\n<meta property=\"og:locale\" content=\"pl_PL\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"LGMD RESEARCHER: Rita Perlingeiro - 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