{"id":2308,"date":"2018-10-24T10:59:24","date_gmt":"2018-10-24T15:59:24","guid":{"rendered":"https:\/\/restruct-lgmd-2021.pantheonsite.io\/?p=2308"},"modified":"2018-10-24T10:59:24","modified_gmt":"2018-10-24T15:59:24","slug":"lgmd-researcher-linda-lowes","status":"publish","type":"post","link":"https:\/\/www.lgmd-info.org\/pt\/researcher-interview\/2018\/10\/24\/lgmd-researcher-linda-lowes\/","title":{"rendered":"INVESTIGADORA LGMD: Linda Lowes"},"content":{"rendered":"

LGMD \"Entrevista em destaque sobre pesquisa\"<\/p>\n

INVESTIGADOR DA LGMD:\u00a0 <\/strong>\u00a0Linda Lowes\u00a0\"\"<\/a><\/p>\n

Filia\u00e7\u00e3o:\u00a0 <\/strong>Nationwide Children's Hospital, Columbus, Ohio, EUA<\/p>\n

Fun\u00e7\u00e3o ou cargo:\u00a0\u00a0<\/strong>Investigador Principal, Instituto de Investiga\u00e7\u00e3o do Nationwide Children's Hospital, Professor Associado do Departamento de Pediatria, Universidade Estatal de Ohio<\/p>\n

Que educa\u00e7\u00e3o e forma\u00e7\u00e3o teve para chegar \u00e0 sua posi\u00e7\u00e3o atual?<\/strong><\/p>\n

Inicialmente, obtive a minha licenciatura na Universidade Estatal de Ohio para me tornar fisioterapeuta. Depois de trabalhar como cl\u00ednico, apercebi-me de que a investiga\u00e7\u00e3o cl\u00ednica me apaixonava, pelo que voltei a estudar na Universidade de Hahnemann para obter o meu doutoramento.<\/p>\n

O que o levou a seguir uma carreira de investiga\u00e7\u00e3o e a estudar a distrofia muscular em particular?<\/strong><\/p>\n

Depois da p\u00f3s-gradua\u00e7\u00e3o, aceitei um lugar de professor na Universidade Estatal de Ohio. Mais uma vez, aprendi rapidamente que a minha paix\u00e3o era a investiga\u00e7\u00e3o cl\u00ednica. Deixei o ensino para me juntar ao Centro de Terapia G\u00e9nica no Instituto de Investiga\u00e7\u00e3o do Nationwide Children's para trabalhar com l\u00edderes na \u00e1rea, como Jerry Mendell, Kevin Flanigan e Louise Rodino-Klapac. Tamb\u00e9m trabalho nas nossas cl\u00ednicas de doen\u00e7as neuromusculares. Ver a ci\u00eancia b\u00e1sica e os doentes a juntarem-se \u00e9 uma oportunidade fant\u00e1stica.<\/p>\n

Que temas est\u00e3o a estudar?<\/strong><\/p>\n

Lidero uma equipa de investigadores que estuda a sele\u00e7\u00e3o e o desenvolvimento de medidas de resultados. Juntamente com Lindsay Alfano, Natalie Miller e Megan Iammarino, estamos a recolher dados da hist\u00f3ria natural de indiv\u00edduos com qualquer forma de LGMD para avaliar que medidas s\u00e3o importantes para o doente, fi\u00e1veis e sens\u00edveis \u00e0 mudan\u00e7a. Os dados da hist\u00f3ria natural tamb\u00e9m servir\u00e3o de controlo externo para que os dados do tratamento possam ser comparados com a taxa tradicional de decl\u00ednio funcional.<\/p>\n

Como \u00e9 que o seu trabalho vai ajudar os doentes? \u00c9 de natureza mais cient\u00edfica ou poder\u00e1 tornar-se um tratamento para a LGMD?<\/strong>s ou MD<\/strong>s em geral?<\/strong><\/p>\n

O nosso trabalho ajudar\u00e1 a acelerar o processo de ensaio cl\u00ednico, garantindo que os dados recolhidos representam com exatid\u00e3o qualquer mudan\u00e7a real nas capacidades. Ter a medida de resultados adequada pode permitir um ensaio mais curto e\/ou mais pequeno.<\/p>\n

O que gostaria que os doentes e outros interessados em LGMD soubessem sobre a investiga\u00e7\u00e3o (os seus pr\u00f3prios projectos e sobre a \u00e1rea em geral)<\/strong><\/p>\n

Estamos sempre \u00e0 procura de pessoas com LGMD para participar nos nossos ensaios de hist\u00f3ria natural. Os volunt\u00e1rios s\u00e3o convidados a realizar actividades com os bra\u00e7os e as pernas, a responder a question\u00e1rios e a testar a sua for\u00e7a muscular. Os riscos de participar nos nossos estudos s\u00e3o muito poucos ou nenhuns e os dados gerados servem para orientar os ensaios de tratamento.<\/p>\n

O que o inspira a continuar a trabalhar neste dom\u00ednio? <\/strong><\/p>\n

Os avan\u00e7os espantosos no trabalho de terapia g\u00e9nica tornam real a possibilidade de podermos ter um impacto dram\u00e1tico nas vidas dos indiv\u00edduos com LGMD durante a minha vida.<\/p>\n

Como \u00e9 que os doentes o podem encorajar e ajudar no seu trabalho?<\/strong><\/p>\n

Por favor, contacte-me em NMDtrialinfo@nationwidechildrens.org<\/a>\u00a0\u00a0 Normalmente, testamos os volunt\u00e1rios em Columbus, Ohio, mas tamb\u00e9m organiz\u00e1mos recolhas de dados em comunidades com um grande n\u00famero de indiv\u00edduos com LGMD ou em confer\u00eancias de doentes.<\/p>","protected":false},"excerpt":{"rendered":"

LGMD \u201cSpotlight Interview on Research\u201d LGMD RESEARCHER:\u00a0 \u00a0Linda Lowes\u00a0 Affiliation:\u00a0 […]<\/p>","protected":false},"author":1,"featured_media":2307,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[91,92],"tags":[],"class_list":["post-2308","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-researcher-interview","category-researcher"],"acf":[],"yoast_head":"\nLGMD RESEARCHER:\u00a0 \u00a0Linda Lowes - LGMD Awareness Foundation<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.lgmd-info.org\/pt\/researcher-interview\/2018\/10\/24\/lgmd-researcher-linda-lowes\/\" \/>\n<meta property=\"og:locale\" content=\"pt_PT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"LGMD RESEARCHER:\u00a0 \u00a0Linda Lowes - 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